Combination Accelerates Outcomes in Early Drug Discovery

WALTHAM, Mass.; Oct. 28, 2021 – X-Chem, the pioneer of DNA-encoded library (DEL) technology and a recognized leader in generating actionable results to drive small molecule drug discovery, today announced the acquisition of Glamorous AI, a leader in artificial intelligence (AI) solutions for drug discovery. Coupling X-Chem’s high-quality DEL data with the innovative AI capabilities of Glamorous AI positions X-Chem as a leading service provider in machine learning-driven drug discovery.

“What AlphaFold did for protein folding, X-Chem and Glamorous AI will do for drug discovery,” said Matt Clark, Ph.D., CEO of X-Chem. “Glamorous AI brings cutting-edge solutions to the entire small molecule drug discovery process. By combining the data-generating power of our leading DEL platform with Glamorous’ AI capability, we will accelerate our partners’ drug discovery programs and get medicines to patients faster.”

The move helps accelerate drug discovery and offers several advantages for our customers, including:

• Revolutionizing the discovery of new medicines — expanded capabilities that save time, reduce risk and yield a higher probability of success from screening to clinical candidate

• The ability to unlock the full potential of rich datasets generated by X-Chem’s technology — rapid identification of high-quality starting points for drug discovery

• The leading AI solution for the entire drug discovery process —merging high-quality, large DEL datasets with sparser medicinal chemistry data to accelerate outcomes

“X-Chem generates billions of high-quality data points with its DEL platform, and we provide the capability to build the best AI to unlock the power of those data. It is when such large datasets come together with a powerful technology like AI that transformation happens. This aligns very well with our vision to democratize access to AI and to provide a fully-integrated service for the biopharma industry,” said Glamorous AI CEO Noor Shaker.

This acquisition, along with the recently announced acquisition of ComInnex, further solidifies X-Chem’s position as the leading provider of innovative solutions in early-stage drug discovery.

About X-Chem
X-Chem, Inc. is a leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market-leading DEL platform to discover novel small molecule leads against challenging, high-value therapeutic targets. X-Chem empowers partners to rapidly screen billions of diverse, drug-like compounds simultaneously and easily identify potent hits that exhibit desired selectivity and mode of action with attractive physicochemical properties. In-house lead optimization services enable clients to progress their compounds directly for even higher quality outputs. Our expertise in medicinal chemistry, custom synthesis and scale-up process chemistry enables us to support all aspects of drug discovery, supporting lead optimization through candidate identification.

About Glamorous AI
Glamorous AI is radically changing how drugs are designed and optimised using our proprietary artificial intelligence platform, RosalindAI. RosalindAI specializes in solving challenges inherent to sparse and noisy data sets that makes the majority of disease-associated targets intractable by existing computational technologies. By building transformative AI solutions and integration with biology and chemistry, we empower organizations to discover new drugs and deliver the right drug to the right patient.

Extending Functional and Global Leadership in Small Molecule Drug Discovery

WALTHAM, Mass.; Oct. 25, 2021 – X-Chem, the pioneer of DNA-encoded library (DEL) technology and recognized leader in generating actionable results to drive small molecule drug discovery, today announced the acquisition of ComInnex, a leading European provider of synthetic chemistry services and novel chemical technologies to support early-stage drug discovery.

With demand for high-quality discovery services increasing across the world, this complementary pairing of a North American leader in DEL and medicinal chemistry with a European leader in synthetic chemistry and custom DEL services delivers the capacity, footprint and expertise to better serve the demands of customers in a global market.

“As a united company, with an increased global presence, we are positioned to meet the increasing demand for innovative chemistry solutions and high-quality discovery services worldwide,” noted Matt Clark, Ph.D., CEO of X-Chem. “The acquisition of ComInnex further extends X-Chem’s expertise and scale of DEL services to help biopharma clients of any size efficiently unlock exponential possibilities in small molecule drug discovery.”

“Combining X-Chem, the world leader and pioneer of high-quality DEL technology, and ComInnex, a leader in the most important trends and novel approaches in early-stage drug discovery chemistry, will yield a powerhouse partner for innovative drug discovery solutions,” commented Alex Drijver, CEO of ComInnex.

ComInnex’s technology expertise in flow chemistry, photochemistry and software development will expand X-Chem’s capabilities supporting the creation and delivery of innovative services for drug developers on a global scale.

About X-Chem
X-Chem, Inc. is the leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market-leading DEL platform to discover novel small molecule leads against challenging, high-value therapeutic targets. X-Chem empowers partners to rapidly screen billions of diverse, drug-like compounds simultaneously and easily identify potent hits that exhibit desired selectivity and mode of action with attractive physicochemical properties. In-house, lead optimization services enable clients to progress their compounds directly for even higher quality outputs. Our expertise in medicinal chemistry, custom synthesis and scale-up process chemistry enables us to support all aspects of drug discovery, supporting lead optimization through candidate identification.

About ComInnex
ComInnex is a synthetic chemistry group passionate about small molecule design and synthesis. Based in Budapest, Hungary, ComInnex supports early-stage drug discovery through a range of products and services, focusing on the latest technologies and adapting to new and emerging trends. The ComInnex platform and toolkit enables rapid design and validation of novel E3 ligase ligands and linkers for targeted protein degradation to accelerate research projects in this area.

Shanghai, August 8 2022 – BioDuro-Sundia, an industry-leading drug discovery, development and commercial service CRDMO backed by Advent International, and X-Chem, a DEL technology pioneer in small molecule drug discovery, jointly announced the launch of DNA Encoded Compound Library (DEL) technology services in China to help more innovative pharmaceutical companies quickly discover small molecule drugs. X-Chem will leverage its powerful DEL technology platform and large collection of novel, diverse lead- and drug-like small molecule compounds to help customers significantly accelerate the discovery of hits and expand their target range. Combined with BioDuro-Sundia’s one-stop drug discovery platform, customers can access world-class discovery technologies and support, covering hit identification and optimization, evaluation of lead and candidate compounds, and quickly advance to preclinical development.

As a pioneer in DEL technology, X-Chem’s libraries contain over 250 billion small molecules. X-Chem has licensed more than 100 research projects to companies in the US, Europe and Japan, comprising over three hundred independent chemical series and more than one thousand validated hit compounds. BioDuro-Sundia will utilize its powerful protein screening platform to assist customers to complete the protein qualification, ensuring that its purity, concentration and degree of aggregation meet the requirements for compound library screening to ensure the best chances for hit identification.

“We are very pleased to collaborate with BioDuro-Sundia in China to explore new and challenging, valuable therapeutic targets,” said X-Chem ‘s CBO, Steffen Helmling. “We believe that X-Chem’ s DEL platform technology, in strong association with BioDuro-Sundia ‘s one-stop new drug discovery development platform, can deliver promising drug leads and will bring higher value returns to our biopharma clients.“

BioDuro-Sundia is an integrated CRDMO providing drug discovery, development and manufacturing services. As an expert in drug discovery, the company has leveraged its more than 18 years of discovery chemistry services and has successfully delivered thousands of projects to date.

“We look forward to working with X-Chem to help our customers discover more novel small molecule leads through the application of DNA Encoded Compound Library (DEL),” said Dr. Xiang Li, Drug Discovery President of BioDuro-Sundia. This collaboration will provide a cutting-edge platform for hit identification in early drug discovery and further expand BioDuro-Sundia’s one-stop new drug discovery and development capabilities. It will also empower innovative Chinese pharmaceutical companies with a more efficient drug discovery mechanism. We believe that through our collaboration with X-Chem scientists, new drug candidates will continue to be discovered and advanced, eventually moving towards the clinic and benefiting patients.”

X-Chem
X-Chem, Inc. is the leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market- leading DEL platform to discover novel small molecule leads against challenging, high-value therapeutic targets. In-house lead optimization services enable clients to progress their compounds directly for even higher quality outputs. Our expertise in medicinal chemistry, custom synthesis and scale-up process chemistry enables us to support all aspects of drug discovery, supporting lead optimization through candidate identification.

Bioduro-Sundia
BioDuro-Sundia, an Advent International portfolio company is a trusted, leading contract research development, manufacturing organization (CRDMO) for over 27 years. We provide our biotech and pharmaceutical partners with fully integrated services to support their efforts from target identification through to commercial drug product manufacturing. The company is based in the US and China with more than 2,500 employees and 10 global sites across 7 cities.

Core expertise includes small and large molecule discovery, development and scale up, support for IND submission, and unique technology platforms such as bioavailability enhancement of insoluble compounds. The one-stop-shop operation helps biotech and pharma partners across the globe to significantly accelerate discovery and de-risk development to create higher value outcomes. We adhere to one global highest standard of compliance and business operation code. Science-driven, customer-oriented, flexible, people focused culture enables us to provide top-tier integrated, fast and flexible tailored services to our customers to meet their unique needs and accelerate development timeline.

Multi-target Collaboration to Focus on Identification of Novel Small Molecules for Anti- inflammatory Applications

BALLERUP, Denmark, and WALTHAM, Mass., US; July 6, 2021 – LEO Pharma A/S, a global leader in medical dermatology and X-Chem, Inc., the global leader in DNA-encoded library (DEL) driven discovery solutions, announced today that they have entered into a research collaboration and license agreement. The goal of the collaboration is to discover and develop novel treatments for dermatological indications.

Under the terms of the agreement, X-Chem will deploy its proprietary DEL platform to identify novel drug-like leads against multiple inflammation targets of interest to LEO Pharma. LEO Pharma has the option to receive exclusive global rights to compounds derived from the partnership and will be responsible for preclinical and clinical research and development. LEO Pharma also retains all rights to commercialization of any potential new medicines emerging from the collaboration.

“At LEO Pharma, we are dedicated to changing the standards of care for people with skin diseases by bringing new innovative treatments forward that are either first or best in class. Supporting this ambition, we are excited to work with the X-Chem team to identify novel small molecule drug leads,” said Thorsten Thormann, Head of Research and early Development. “X-Chem’s DEL platform technology is a powerful approach giving us increased capabilities to feed our innovative project portfolio.”

X-Chem CEO Matt Clark, Ph.D., said, “We are delighted to partner with LEO Pharma, a global leader in medical dermatology R&D. We look forward to a productive partnership with many tractable drug leads.”

About LEO Pharma
LEO Pharma helps people achieve healthy skin. The company is a leader in medical dermatology with a robust R&D pipeline, a wide range of therapies and a pioneering spirit. Founded in 1908 and owned by the LEO Foundation, LEO Pharma has devoted decades of research and development to advance the science of dermatology, setting new standards of care for people with skin conditions. LEO Pharma is headquartered in Denmark with a global team of 6,000 people, serving 93 million patients in 130 countries. In 2020, the company generated net sales of DKK 10,133 million. For more information please visit www.LEO-Pharma.com.

About X-Chem
X-Chem, Inc. is the leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market-leading DEL platform to discover novel small molecule leads against challenging, high-value therapeutic targets. X-Chem empowers partners to rapidly screen billions of diverse, drug-like compounds simultaneously and easily identify potent hits that exhibit desired selectivity and mode of action with attractive physicochemical properties. In-house lead optimization services enable clients to progress their compounds directly for even higher quality outputs. Our expertise in medicinal chemistry, custom synthesis and scale-up process chemistry enables us to support all aspects of drug discovery, supporting lead optimization through candidate identification. For more about X-Chem, visit x-chemrx.com.

Contacts

LEO Pharma
Henrik Kyndlev
HDTDK@leo-pharma.com
+45 3140 6180

X-Chem
Steffen Helmling, PhD
bd@x-chemrx.com
+1 781 4196900

Flexible and Cost-Effective Solution for Screening Billions of Small Molecules

WALTHAM, Mass.; May 11, 2021 (Business Wire) – X-Chem, the industry-leading provider of DNA-encoded library (DEL)-based discovery services, today announced the global launch of its OpenDEX solution. This new offering provides flexible access to the high-quality libraries, experienced DEL operators and powerful informatic tools that make up the X-Chem discovery platform.

Pharmaceutical, biotech and academic researchers can now unlock exponential possibilities in their small molecule drug discovery programs. OpenDEX gives X-Chem’s clients open access to the full scope of the company’s DEL screening output, allowing them to rapidly prioritize efforts on the most promising, novel and attractive compounds. When coupled with X-Chem’s high-quality synthetic chemistry, hit-to-lead and lead optimization medicinal chemistry services, OpenDEX becomes the method of choice for rapid lead generation with an increased probability of success.

“Emerging pharma and biotech companies look to access state-of-the-art DEL screening in a cost-effective way,” said X-Chem CEO Matt Clark. “Our mission is to deploy the power of DEL to benefit a diverse range of partners. Our new OpenDEX partnership model will put the power of our DEL screening platform into the hands of more clients.”

X-Chem has also unveiled a new brand and website reflective of its broader offerings like OpenDEX. They include the expansion of its comprehensive hit-to-lead and lead optimization solutions from the company’s recent acquisition and integration of Intellisyn and AviSyn, which enable partners to quickly move from DEL screen to rapid initiation of a full drug discovery program.

To learn more about how you can take the lead and drive discovery with X-Chem OpenDEX, visit our website.

About X-Chem
X-Chem, Inc. is the leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market-leading DEL platform to discover novel small molecule leads against challenging, high-value therapeutic targets. X-Chem empowers partners to rapidly screen billions of diverse, drug-like compounds simultaneously and easily identify potent hits that exhibit desired selectivity and mode of action with attractive physicochemical properties. In-house lead optimization services enable clients to progress their compounds directly for even higher quality outputs. Our expertise in medicinal chemistry, custom synthesis and scale-up process chemistry enables us to support all aspects of drug discovery, supporting lead optimization through candidate identification. For more about X-Chem, visit x-chemrx.com.

Collaboration Includes Licensing of Preclinical Small Molecule Program 

WALTHAM, Mass.; Feb. 2, 2021 (Business Wire) – X-Chem, Inc., a global leader in DNA-Encoded Library (DEL) technology to identify novel drug leads, announced today that it has entered into a research collaboration and license agreement with Genentech, a member of the Roche Group. The goal of the collaboration is to discover and develop novel small molecule treatments in oncology. 

Under the terms of the agreement, X-Chem will deploy its proprietary DEL platform to identify novel drug-like leads against multiple oncology targets of interest to Genentech and may also conduct hit-to-lead optimization for the programs. In addition, X-Chem grants Genentech an exclusive license to an existing preclinical, small molecule oncology program, consisting of several series of novel compounds previously identified by X-Chem using its DEL platform. 

Genentech retains exclusive global rights to compounds derived from the collaboration and will be responsible for further research, development and commercialization of any potential new medicines emerging from the collaboration. X-Chem will receive an upfront payment and is eligible to receive research, development and regulatory milestone payments, based upon certain predefined events. X-Chem is also eligible to receive royalties from the sales of medicines resulting from the collaboration. 

“X-Chem’s approach to DEL libraries and screening complements Genentech’s small molecule drug discovery efforts and has the potential to help overcome long-standing challenges in drugging difficult oncology targets,” said James Sabry, M.D., Ph.D., global head of pharma partnering, Roche. “We look forward to working with X-Chem to discover molecules that we hope could positively impact the lives of people with cancer.” 

Matt Clark, Ph.D., Chief Executive Officer of X-Chem, said, “We are very excited to enter into this new partnership with Genentech, one of the most respected and innovative developers of cancer treatments in the biopharmaceutical industry. The collaboration further demonstrates the potential of X-Chem’s DEL platform to deliver novel tractable drug leads and provide value to our partners and clients and, in turn, strengthen their drug development pipelines.” 

About X-Chem
X-Chem is the industry-leading provider of DNA-Encoded Library (DEL)-based discovery services. X-Chem has entered into drug discovery partnerships with numerous pharmaceutical companies, established and early-stage biotechnology companies, as well as research institutes and universities resulting in the licensing of hundreds of novel hits and leads across many target classes and therapeutic areas. X-Chem’s clients and licensees include AbbVie, AstraZeneca, Bayer, Bristol-Myers Squibb, Genentech, Gilead, Janssen, Maruho, MD Anderson Cancer Center, Otsuka, and Vertex, among others. For further information, please visit: www.x-chemrx.com. 

• Acquisition allows X-Chem to offer a more comprehensive, integrated, screen-to-lead drug discovery process to pharma and biotech clients
• IntelliSyn’s Founder and CEO Jeffrey Albert to join X-Chem management team

Waltham, Mass., US: Jan. 26, 2021 (Business Wire) – X-Chem, Inc. (X-Chem), the industry-leading provider of DNA-Encoded Library (DEL)-based discovery services, has acquired IntelliSyn, a Montreal-based drug discovery services company and its US-based sister company, AviSyn. The transaction will enable the Company to offer a complete, seamless solution for screening, hit validation and lead optimization on existing and new markets. Financial details of the deal have not been disclosed.

Leveraging a proprietary DEX platform with libraries containing over 200 billion small molecules, X-Chem discovers new drug leads for biopharma clients. IntelliSyn’s services will complement X-Chem’s service offering as an additional downstream part of the drug discovery process, primarily in the field of medicinal chemistry, custom synthesis and scale-up process chemistry, supporting lead optimization through candidate identification.

“The acquisition of IntelliSyn and AviSyn will allow us to significantly extend our capabilities to support drug discovery. This will result in a more streamlined offering to our clients. Fast drug discovery is essential in today’s biopharma industry and our new integrated offering will support our clients by accelerating this phase of their drug discovery journey,” said Matt Clark, Chief Executive Officer at X-Chem.

IntelliSyn’s Founder and CEO Jeffrey Albert will join the X-Chem management team.

“We are excited to join X-Chem and make real impact on our partners’ drug discovery efforts. IntelliSyn and X-Chem share a common dedication to innovation, quality, and scientific excellence. Together we will create a differentiated approach to drug discovery,” said Jeffrey Albert, Founder and CEO at IntelliSyn.

X-Chem’s proprietary DEL technology allows customers to screen billions of compounds simultaneously against a single biological target; faster than conventional high-throughput screening (HTS) methods. The Company has licensed over 70 research programs, comprising hundreds of novel chemical entities, to companies throughout the US, Europe, and Japan.

Fairmount Partners, an investment bank based in Philadelphia, PA, introduced the parties and provided investment banking advisory services to the shareholders of IntelliSyn and Avisyn.

Strategic Legal Inc., acted as lead counsel for the shareholders of IntelliSyn and Avisyn. Richter LLP and CFLA s.e.n.c.r.l. acted as the shareholders’ tax advisors.

Stikeman Elliott LLP provided legal advice, RSM Global provided tax, financial and accounting advice, Atlantic Global Risk Corporation provided insurance advice, and Freeman and Clarke, Inc. provided IT advice to X-Chem.

About X-Chem
X-Chem is the industry-leading provider of DNA-Encoded Library (DEL)-based discovery services. X-Chem has entered into drug discovery partnerships with numerous pharmaceutical companies, established and early-stage biotechnology companies, as well as research institutes and universities resulting in the licensing of hundreds of novel hits and leads across many target classes. X-Chem’s clients and licensees include AbbVie, AstraZeneca, Bayer, Bristol-Myers Squibb, Gilead, Janssen, Maruho, MD Anderson Cancer Center, Otsuka, Roche, Vertex, among others. For further information, please visit: www.x-chemrx.com 

About IntelliSyn and AviSyn
IntelliSyn is among the leading providers of medicinal chemistry support in North America.  Our team of experienced scientists (>80% PhD), at our state-of-the-art facilities in Montreal, specializes in identifying novel leads and optimizing them as successful clinical candidates for our collaborators across Major Pharma and Biotech.  We provide discovery support (computational chemistry, design, synthesis, and DMPK) where innovation, intellectual property security, and proven delivery-expertise are needed on an expert basis.  Our discipline expertise ranges across CNS, oncology, metabolic diseases as well as other specialized areas including structure-based design, GPCR modulators, and ion channel modulators. Avisyn is the US-based affiliate which provides medicinal chemistry support on an in-sourced basis.

Further information:

Instinctif Partners

Agnes Stephens – agnes.stephens@instinctif.com

Ross Gillam – ross.gillam@instinctif.com

Nick Corrin – nick.corrin@instinctif.com

Paris and Waltham, Mass.; Jan. 6, 2021 (Business Wire) – Servier, a global pharmaceutical Group and X-Chem, Inc., a privately held drug discovery company announced today a partnership to identify and develop novel small molecules for the treatment of neurological disorders.

Under the terms of the multi-target agreement, X-Chem will utilize its DNA-Encoded library (DEL) platform to identify novel small molecule leads directed towards Central Nervous System (CNS) targets of interest to Servier. The parties may further progress identified leads into protein-degrading chimeric molecules, with X-Chem leading the design and synthesis of bispecific degrader molecules. Servier will be responsible for advancing any promising candidates through preclinical and clinical development and retains all rights for the commercialization of any products resulting from the collaboration. X-Chem will receive research payments and is entitled to additional payments upon the achievement of certain success milestones.

“Our partnership with X-Chem supports Servier’s drive for innovative drug discovery approaches towards new treatments for the benefit of patients suffering from neurological diseases. Combining our expertise gives us a truly valuable opportunity to advance the expanding internal program of drug discovery projects here at Servier, with the ultimate goal of bringing forward new and effective treatments to slow the progression of these devastating diseases,” said Ross Jeggo, Head of the Neurology & Immuno-Inflammation therapeutic area at Servier.

“We are delighted that Servier has chosen X-Chem as its partner for drug discovery in this challenging therapeutic area.” said Matt Clark, Chief Executive Officer at X-Chem. “We look forward to a long-term scientific collaboration with the Servier team to make advances in the treatment of neurological diseases.”

About Servier
Servier is an international pharmaceutical company governed by a non-profit foundation, with its headquarters in France (Suresnes). With a strong international presence in 150 countries and a total revenue of 4.6 billion euros in 2019, Servier employs 22,000 people worldwide. Entirely independent, the Group invests on average 25% of its total revenue (excluding generics) every year in research and development and uses all its profits for its development. Corporate growth is driven by Servier’s constant commitment in five areas of excellence: cardiovascular, immune-inflammatory, and neurodegenerative diseases, cancer and diabetes, as well as by its activities in high-quality generic drugs. Servier also offers eHealth solutions beyond drug development. More information: www.servier.com

About Servier BioInnovation
Servier’s innovation efforts in the US are enhanced by Servier BioInnovation, a joint initiative between Servier Group R&D and Business Development & Licensing, focused on external innovation in the U.S. BioInnovation’s mission includes identifying early-stage R&D opportunities and expediting BD&L activities, increasing the group’s visibility and attracting talent as well as establishing R&D partnerships in key life science innovation ecosystems. https://www.servier.us/#bioinnovation

About X-Chem
X-Chem is the industry-leading provider of DNA-Encoded Library (DEL)-based discovery services. X-Chem has entered into drug discovery partnerships with numerous pharmaceutical companies, established and early-stage biotechnology companies, as well as research institutes and universities resulting in the licensing of hundreds of novel hits and leads across many target classes. X-Chem’s clients and licensees include AbbVie, AstraZeneca, Bayer, Bristol-Myers Squibb, Gilead, Janssen, Maruho, MD Anderson Cancer Center, Otsuka, Roche, Vertex, among others. For further information, please visit: www.x-chemrx.com

Waltham, Mass – January 4, 2021 – X-Chem Inc. (X-Chem), the global leader in DNA-Encoded Library (DEL) technology to identify novel drug leads, announced today that Otsuka Pharmaceutical Co., Ltd. (Otsuka) has licensed a second drug discovery program from X-Chem.
Under the terms of the parties’ multi-target Drug Discovery Research and License Collaboration, Otsuka exercised the option to exclusively license this additional program, which comprises a promising highly-specific novel small molecule drug lead for a very challenging target. The license is a direct result of X-Chem screening its DNA-encoded libraries containing hundreds of billions of drug-like small molecules, and using its advanced proprietary informatics platform to identify novel drug leads for the Otsuka target. Otsuka is solely responsible for the conduct of clinical trials with drug candidates derived from licensed compounds, and retains exclusive rights to globally commercialize any resulting products.
“X-Chem is proud to issue our second compound license to Otsuka,” said Matt Clark, CEO of X-Chem. “Our partnership with Otsuka has been a success due to the collaborative engagement and rigorous determination of the joint research teams, who achieved our mutual goal of identifying hit compounds for extremely difficult-to-drug targets. We look forward to continued engagement with Otsuka in the coming years as X-Chem continues to expand our leadership position in the drug discovery field.”