Smarter Discovery. Real Results.

At X-Chem, we do more than screen compounds. We help you make confident decisions that move science forward. Our integrated platform combines DNA-encoded libraries, medicinal chemistry, advanced modeling and proprietary AI into a powerful and precise discovery engine.

Everything is connected through chemomics, our approach to unlocking value from every data point. Whether you’re exploring a new target or refining a lead, we help you discover high-quality molecules with greater speed, insight and control.

With more than 100 licensed programs, eighteen clinical candidates and an industry-leading hit success rate across diverse target classes, we bring clarity to complex challenges.

What Powers Our Platform

Chemomics in Practice

Our discovery model is not a patchwork of tools. It is a unified engine that transforms large-scale screening data into clear next steps, reducing risk and accelerating progress.

DNA-Encoded Libraries

With 250B+ compounds, our DEL platform explores broad chemical space with high-quality signal. Libraries are designed by chemists, guided by modeling, and optimized to deliver what matters.

Medicinal Chemistry

We don’t stop at hits. Our chemists partner with screening and modeling teams to design, refine, and optimize compounds with the right properties at the right time.

Computational Science and AI

AI and modeling tools, including ArtemisAI and HITMiner, guide compound selection, prioritize series, and flag liabilities early — improving hit quality and speeding optimization.

Why X-Chem?

  • 250B+ DNA-tagged molecules across 100+ diverse libraries
  • Libraries designed for diversity, quality, and developability, not just numbers
  • Integrated AI + computational modeling to guide selection and design
  • 100+ licensed programs, >900 chemical series, 1,000+ validated hits
  • 8 Clinical compounds from X-Chem DEL
  • End-to-end chemistry expertise to accelerate candidate development

The Values Behind the Science

Mission

To apply the most advanced drug discovery platform in the world to create molecules that improve lives.

Vision

To be the discovery partner that changes what is possible in small molecule therapeutics.

Our Values
  • Innovation – We explore bold science to create value and efficiency.
  • Collaboration – We listen first, then act with purpose.
  • Integrity – We own our work and operate with transparency.
  • Excellence – We aim higher. Always.
  • Empowerment – We believe decisions are stronger when made together.

Our Global Presence

With teams in North America and Europe, our labs support the full scope of discovery, from hit finding to candidate nomination. Every program is led by experienced scientists, managed with transparency, and designed to meet your goals.