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Scientific Publication

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    Chemical ligation methods for the tagging of DNA-encoded chemical libraries.

    Chemical ligation methods for the tagging of DNA-encoded chemical [...]

  • Scientific Publication

    Discovering Small Molecule Compounds through The DNA Encoded Library Technology

    Discovering Small Molecule Compounds through The DNA Encoded Library [...]

  • Scientific Publication

    Bigger is Better

    “The vision is that when the library is big [...]

  • Scientific Publication

    Overview of Recent Progress in Protein-Expression Technologies for Small-Molecule Screening

    Overview of Recent Progress in Protein-Expression Technologies for Small-Molecule [...]

  • Scientific Publication

    Roles of TRPA1 in Pain Pathophysiology and Implications for the Development of a New Class of Analgesic Drugs

    The Transient Receptor Potential A1 (TRPA1) ion channel has [...]

  • Scientific Publication

    Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags

    Universal strategies for the DNA-encoding of libraries of small [...]

  • Scientific Publication

    Multiple roles of transient receptor potential (TRP) channels in inflammatory conditions and current status of drug development

    During inflammation, several Transient Receptor Potential (TRP) channels are [...]

  • Scientific Publication

    Fragment-Based Drug Discovery Approaches

    This issue of Current Topics in Medicinal Chemistry focuses [...]

  • Scientific Publication

    An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca’s drug discovery programmes

    Fragment-based lead generation (FBLG) has recently emerged as an [...]

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