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Portfolio

Portfolio

  • Scientific Publication

    Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

    The activity of the secreted phosphodiesterase autotaxin produces the [...]

  • 2020, Press Releases

    X‑Chem Announces Achievement of Milestone In Orexia Collaboration

    Download PDF Waltham, Mass – July 22, 2020 [...]

  • Scientific Publication

    Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding

    DNA-encoded small molecule libraries (DELs) have enabled discovery of [...]

  • 2020, Press Releases

    Study Published in the Journal of Medicinal Chemistry Demonstrates the Power of Machine Learning to Unlock New Chemistry and Biology to Treat Disease

    Download PDF Study Published in the Journal of [...]

  • 2020, Press Releases

    GHO Capital Acquires X‑Chem, the Leading Provider of DNA-Encoded-Library-Mediated Drug Discovery Services

    Download PDF  Matt Clark named new Chief Executive [...]

  • 2020, Press Releases

    X‑Chem Announces Licensing of a Drug Discovery Program to Otsuka

    Download PDF Waltham, Mass – May 20, 2020 [...]

  • Patents

    Fulcrum Therapeutics, Inc., USA .; Macrocyclic azolopyridine derivatives as EED and PRC2 modulators and their preparation

    The invention relates to modulators of Embryonic Ectoderm Development [...]

  • 2020, Press Releases

    ALK-Abelló and X‑Chem Announce Drug Discovery Collaboration

    WALTHAM, Mass. – February 5, 2019 – X-Chem, Inc. [...]

  • 2020, Press Releases

    ZebiAI Therapeutics, Inc. and X‑Chem Enter into Strategic Agreement to Enable Validation of Novel Therapeutic Targets and Acceleration of Drug Candidate Discovery

    Download PDF New venture capital-backed artificial intelligence company [...]

  • Patents

    Achaogen, Inc., USA .; Modular synthesis of aminoglycosides as antibacterial agents

    The present disclosure relates to novel methods for preparing [...]

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      • Case Studies
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      • Targeted Protein Degradation Molecular Glues
      • Covalent Inhibitors
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      • GPCR Discovery
    • DEL Track Record
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