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Portfolio

Portfolio

  • 2025, Press Releases

    X‑Chem Strengthens Executive Team with Strategic Finance and HR Appointments

    New leaders join X-Chem to support operational excellence and [...]

  • Insert Sheet

    DEL for RNA Targets

    Mirror-image DEL Screen: Best-in-class Hit Discovery Solutions RNA-targeting [...]

  • Podcast

    Under the Surface: The Power of Automation in Drug Development

    Rebecca Swett, Director of Computational Chemistry at X-Chem, joins Host [...]

  • 2025, Press Releases

    Axxam and X‑Chem announce collaboration to broaden access to DNA-Encoded Library screening for early drug discovery

    Milan, Italy and Waltham, MA, USA, May 8, 2025 [...]

  • 2025, Press Releases

    X‑Chem Expands Strategic Collaboration with Orion Pharma to Accelerate Orion’s Early Drug Discovery from Hit to Candidate

    Waltham, MA, April 30, 2025 – X-Chem, a global leader [...]

  • Scientific Poster

    Discovery of highly selective ligands for the Bcl-2 family of proteins using DNA-Encoded Chemical Libraries

    DNA-encoded chemical library (DEL) technology enables the efficient screening [...]

  • Scientific Poster

    DEL Screening and ML for Hit ID for the WD40-Repeat Oncology Targets DCAF1, WDR5 and WDR12

    Training machine-learned models using DNA-Encoded Chemical Library screening data [...]

  • Scientific Poster

    Mirror-image RNA-targeted DEL Screens

    Discovering RNA-binding small molecules is a formidable challenge with [...]

  • Patents

    Inhibitors of P97 Protein and Methods of Use

    Described herein are compounds and compositions useful for preventing [...]

  • Scientific Publication

    Building Efficient Diastereo- and Enantioselective Synthetic Routes to trans-Cyclopropyl Esters for Rapid Lead Scale-Up

    Cyclopropanes play an important role in drug discovery, and [...]

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      • Case Studies
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      • Targeted Protein Degradation Molecular Glues
      • Covalent Inhibitors
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      • GPCR Discovery
    • DEL Track Record
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