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Portfolio

Portfolio

  • Scientific Poster

    Discovery of Reversible Covalent Binders to Bfl-1 using DNA-Encoded Chemical Libraries

    DNA-encoded chemical library (DEL) technology enables the efficient screening [...]

  • 2024, Press Releases

    X‑Chem Announces Candidate Milestone

    WALTHAM, Mass.; Sept. 17, 2024 (Business Wire) – X-Chem, a [...]

  • 2024, Press Releases

    Evotec and X‑Chem Collaborate to Accelerate Early-Stage Drug Discovery

    WALTHAM, Mass.; Sept. 5, 2024 – Evotec SE (Frankfurt Stock Exchange: EVT, [...]

  • 2024, Press Releases

    Cancer Research Horizons appoints Therapeutic Innovation board to drive drug discovery strategy

    Carlos Garcia-Echeverria, Katharina Kreymborg and Karen Lackey become members [...]

  • Scientific Publication

    Negishi-coupling-enabled synthesis of α-heteroaryl-α-amino acid building blocks for DNA-encoded chemical library applications

    Amino acids are vital motifs in the domain of [...]

  • 2024, Press Releases

    X‑Chem Strengthens Its Data-Driven Discovery Services With New CBO Appointment

    WALTHAM, Mass.; June 20, 2024 (Business Wire) – Small molecule [...]

  • Article

    New Method Allows Easy Synthesis of Valuable Amine-Containing Pharmaceuticals

    Scientists from X-Chem, in collaboration with researchers at AstraZeneca, [...]

  • Scientific Poster

    Discovery of Pks13 Inhibitors for the Treatment of Tuberculosis through DNA-encoded Chemical Library Screening

    Here we report the use of DNA encoded Library [...]

  • Scientific Publication

    Identification, Evaluation and Optimization of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen

    Bfl-1 is over-expressed in both hematological and solid tumors, [...]

  • Scientific Publication

    Raney Nickel-Catalyzed Deuterium Labeling of Nitrogen-Containing Heterocycles and Pharmaceuticals under Continuous Flow Conditions

    Deuterium-labeled compounds play a pivotal role in physical organic [...]

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      • Case Studies
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      • Targeted Protein Degradation Molecular Glues
      • Covalent Inhibitors
      • Kinases
      • GPCR Discovery
    • DEL Track Record
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    • Flexible Project Models
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