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Portfolio

Portfolio

  • Scientific Poster

    Enabling Metabolic Disease Research With DNA-encoded Library Screening: Case Study on HAO1

    For numerous rare diseases, the steep costs associated with [...]

  • Scientific Publication

    A General Strategy for the Amination of Electron-rich and Electron-poor Heteroaromatics by Desaturative Catalysis

    The introduction of alkylamines onto heteroaromatics is integral to [...]

  • Article

    X‑Chem Wins 2024 Drug Discovery Chemistry Best of Show Award

    X-Chem’s “DELability” offering is recognized as an exceptional innovation [...]

  • Scientific Poster

    Advancements in Isotopic Labeling: H/D Exchange on N-Heterocycles and the Development of a 13CO2 Generator

    Isotopically labeled compounds play a crucial role in material [...]

  • Scientific Publication

    Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered using DNA-Encoded Chemical Library Screening

    DNA-encoded chemical library (DEL) technology provides a time- and [...]

  • Podcast

    2-Aza- and 2-oxabicyclo[2.1.1]hexane derivatives as factor XIIA enzyme inhibitors

    The present invention provides compounds of formula (I): Formula [...]

  • Scientific Publication

    Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds

    Dysregulation of IL17A drives numerous inflammatory and autoimmune disorders [...]

  • 2024, Press Releases

    X‑Chem Adds Chief Technology Officer to Bolster Its Digital Drug Discovery Strategy

    WALTHAM, Mass.; April 2, 2024 (Business Wire) – X-Chem, the leading provider [...]

  • Scientific Publication

    DNA-Encoded Library Technology ─ A Catalyst for Covalent Ligand Discovery

    The identification of novel covalent ligands for therapeutic purposes [...]

  • Scientific Poster

    Discovery of highly selective ligands with unique binding modes for challenging oncology targets using DEL

    DNA-encoded chemical library (DEL) technology enables the efficient screening [...]

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  • Why X-Chem
    • Our Difference
    • Discovery Philosophy
    • Chemomics
  • Insights & Results
    • Resource Center
      • All Resources
      • Case Studies
      • Press Releases
      • Scientific Posters
      • Scientific Publications
    • News
    • Target Classes
      • Protein-Protein Interactions
      • Targeted Protein Degradation Molecular Glues
      • Covalent Inhibitors
      • Kinases
      • GPCR Discovery
    • DEL Track Record
    • MedChem Track Record
  • Ways to Partner
    • Flexible Project Models
      • CandidateBuilder
      • HitBuilder
      • LeadBuilder
    • Fee for Service Packages
    • Platform Enablement
    • Strategic Collaborations
  • Our Technology
    • DEL Screening
    • Medicinal & Synthetic Chemistry
    • Research Products
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