This study describes a novel series of UDP-N-acetylglucosamine acyltransferase [...]

Libraries of DNA-Encoded small molecules created using combinatorial chemistry [...]

Inhibition of hydroxy acid oxidase 1 (HAO1) is a [...]

An approach of building block (BB) inclusivity and atom [...]

Publication: J.Med.Chem 2021 Bispecific degraders (PROTACs) of ERα are expected [...]

J. Med. Chem. 2021 Mer is a member of [...]

Publication: Nature The structural mechanisms of single-pass transmembrane enzymes remain [...]

Publication: Nature Protease-activated receptor-2 (PAR2) has been implicated in multiple [...]

The activity of the secreted phosphodiesterase autotaxin produces the [...]

DNA-encoded small molecule libraries (DELs) have enabled discovery of [...]