DCAF1 is a substrate receptor of two distinct E3 [...]

The c-MET receptor tyrosine kinase has received considerable attention [...]

Over the past decade, DNA-encoded libraries (DELs) have emerged [...]

This study describes a novel series of UDP-N-acetylglucosamine acyltransferase [...]

Libraries of DNA-Encoded small molecules created using combinatorial chemistry [...]

Inhibition of hydroxy acid oxidase 1 (HAO1) is a [...]

An approach of building block (BB) inclusivity and atom [...]

Publication: J.Med.Chem 2021 Bispecific degraders (PROTACs) of ERα are expected [...]

J. Med. Chem. 2021 Mer is a member of [...]

Publication: Nature The structural mechanisms of single-pass transmembrane enzymes remain [...]