Matthew A. Clark, Ph.D.

Matt is a world-recognized innovator and leader in the DNA-encoded library (DEL) field. He was part of X-Chem’s founding team and served as VP of chemistry and SVP of research prior to his appointment to the CEO position. Under his scientific leadership, the company developed from a niche chemical discovery platform to a world-leading drug discovery engine serving the biopharma industry. Before joining X-Chem, Matt was director of chemistry at GlaxoSmithKline, where he led the group responsible for design and synthesis of early-iteration DELs. He began his professional career at Praecis Pharmaceuticals, where he played a key role in the early development and implementation of technologies that would become the basis for DEL. Matt is a thought leader in the DEL space, with numerous patents and key DEL publications to his name. He received his B.S. in biochemistry from the University of California, San Diego, holds a Ph.D. in chemistry from Cornell University, and conducted postdoctoral studies at the Massachusetts Institute of Technology.

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