X-Chem’s expertise in advanced chemistry methods reaches far beyond DNA-encoded library (DEL) synthesis. We have extensive experience in applying our innovative thinking to difficult problems in chemical synthesis.

Our clients rely on us to solve their most difficult and IP-sensitive synthetic challenges. Our experience spans the gamut of chemotypes and applications, whether it be synthesizing an array of bispecific degraders or scouting scale-up routes for a development candidate. Furthermore, we are leaders in bringing the most modern and powerful synthetic methodologies to bear, including chiral SFC, photoredox chemistry, asymmetric catalysis and flow chemistry. We have a strong track record in successfully developing shorter and more efficient multistep processes, frequently through novel enantioselective methods.

We can help our clients in a number of areas, including:

  • Bispecific degraders
  • Peptides and peptidomimetics
  • Macrocycles
  • Array chemistry
  • Tool compounds
  • Process route scouting
  • Scale-up to 500g
  • Off-DNA synthesis and follow-up

If you have a difficult chemistry problem that would benefit from an innovative approach, consult the leaders in chemistry innovation: X-Chem.