Unsurpassed Solutions for Complex Chemistry Challenges 

At X-Chem, our chemistry team has a reputation for providing the highest quality service, built on over 30 years of experience. We are known for tackling the most difficult and IP-sensitive synthetic chemistry challenges, offering industry-leading solutions tailored to your needs. With a strong focus on innovation and a team of dedicated synthetic chemists, we have the experience and end-to-end capabilities to produce the specific compound to meet your custom synthesis needs. 

Broad Range of Custom Synthetic Chemistry Services 

With X-Chem’s extensive expertise, we can address a wide spectrum of custom synthesis requirements: 

  • Design and synthesis of linkers and ligands for targeted protein degradation
  • Synthesis of full or partial protacs (chimeras)
  • Synthesis of peptides and peptidomimetics 
  • Exploration of macrocyclic chemistry
  • Implementation of an array chemistry approaches
  • Creation of tool compounds for various applications
  • Process route scouting and optimization
  • Scalability up to 500 grams
  • Expertise in off-DNA synthesis and follow-up studies 
  • Variety of different photochemistry instruments and solutions including photochemistry in batch and in flow reactors
  • Application of flow chemistry for solving otherwise problematic chemical synthesis and the development batch to flow synthesis protocols

Extensive Expertise and Robust Reputation 

We have earned a stellar reputation for our exceptional track record and commitment to excellence. With our expanding global team of highly skilled synthetic chemists, we consistently deliver outstanding results that meet the highest professional standards. Our dedication to accuracy, clear communication and timely execution ensures that your customized synthetic chemistry project is handled with the utmost care and precision. 

Seamless Collaboration and Integration 

We understand the importance of seamless collaboration, and our multisite projects and workflows are integrated flawlessly across our Budapest, Waltham and Montreal sites. By utilizing common electronic laboratory notebooks (ELNs), laboratory information management systems (LIMS) and enterprise resource planning (ERP) tools, we ensure efficient management of your custom synthesis project and streamlined communication throughout the entire process. 

Cutting-Edge Facilities and Quality Assurance 

With leading-edge instruments and advanced technologies, we boast fully equipped synthetic chemistry laboratories capable of handling your project at scales up to hundreds of grams. Our comprehensive range of instrumentation, including advanced flow chemistry instruments, purification technologies and analytical instruments, allows us to deliver your high-quality compound with confidence. Each final compound undergoes rigorous quality control, including thorough LC-MS and NMR analysis, to ensure their integrity and purity. 

When your complex chemistry problem demands an advanced approach, trust the leaders in chemistry innovation.