X‑Chem’s New ReadiDELs Offer a Shorter Route to the Benefits of DEL Innovation

May 6, 2022

The last two years have seen X-Chem transform itself from a boutique DEL screening shop to an integrated drug discovery...


Getting Back to In Person

April 13, 2022

I recently had the pleasure of taking a trip to the West Coast to meet with several X-Chem clients. They...


A Track Record of Success

March 15, 2022

For those who didn’t notice, X-Chem underwent a major rebranding in mid-2021. We rolled out our new website, logo, color...


Where AI Is Heading and Why X‑Chem Is Positioned to Lead

February 15, 2022

The use of AI to increase the efficiency of drug discovery has increased considerably over the past few years. Drug...


Software and Science Go Hand in Hand at X‑Chem: Informatics Tools for a Scalable and Effective DEL Platform

January 13, 2022

From the very beginnings of X-Chem, we recognized the need to invest in software capabilities. DNA-encoded library (DEL) technology generates...


What a Year! X‑Chem 2021 in Review

December 7, 2021

The month of December is often a time to take stock and assess the accomplishments of the past year. As...


X‑Chem’s DNA-Encoded Library (DEL) Platform Enables the Discovery of Lead-Like Molecules for Medicinal Chemistry Progression

November 10, 2021

Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening X-Chem’s DNA-encoded library (DEL)...


Mechanistic Understanding of a Difficult GPCR Aided by DEL and Medicinal Chemistry

October 18, 2021

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition GPCRs are important targets to investigate, not just for...


Beyond DNA-Encoded Library Screening: How Integrated Services Improve the Outcome of the Drug Discovery Program

September 14, 2021

As the industry leader in DNA-encoded library (DEL) technology, X-Chem’s core business has been the hunt for novel small molecule...


Focusing on building blocks and properties is the best way to design better DNA-Encoded Libraries (DELs)

August 3, 2021

It seems to be a common experience. Your new drug discovery project has accessed a DEL screen and you’re eagerly...