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Applying DNA-Encoded Chemistry to the Discovery of Irreversible Covalent Inhibitors

July 15, 2021

Some of the most commonly used drugs elicit their therapeutic effects by forming covalent bonds with their targets; examples include...

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Proof of Concept: DEL for PROTACs

June 15, 2021

DNA-Encoded Chemical Library Screening Is a Great Tool for Identifying Novel Binders Suitable for Bispecific Degraders The Value of DEL...

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Truncations, Side Products and Truth in Labeling for DNA-Encoded Libraries: A Cautionary Tale

May 11, 2021

Did you ever search a library catalog, dutifully note the location of a book that is allegedly not checked out,...