Through the Lens of a Lead Discovery Scientist: Enabling Hit Identification Through DNA-Encoded Libraries

February 15, 2023

The phrase “you miss 100% of the shots you don’t take” was originally coined by Wayne Gretzky about scoring goals...


A Year of Driving Small Molecule Discovery

January 3, 2023

2022 was a big year here at X-Chem, so as we embark into 2023 it seems like a good time...


The 10th International Symposium on DNA-Encoded Chemical Libraries

November 30, 2022

Earlier this month I had the pleasure of attending the 10th International Symposium on DNA-Encoded Chemical Libraries (informally referred to...


New Directions in DEL Research

October 24, 2022

At X-Chem, we make it a priority to stay engaged with the latest advances in DNA-encoded library (DEL) technology and...


Solution DEL and Bead DEL: Two Tools for Advancing Drug Discovery

September 13, 2022

In 1992, the late professors Brenner and Lerner were the first to publish the concept of encoding synthetic chemistry with...


DELability – Protein Assessment for DEL Screening

July 20, 2022

Over the last 5 years, biopharma has fully embraced the use of DNA-encoded libraries (DELs) for hit identification for all...


Does Size Matter in DEL Screening?

June 23, 2022

One of the most attractive aspects of DNA-encoded library (DEL) technology is the vast number of compounds that can be...


X‑Chem’s New ReadiDELs Offer a Shorter Route to the Benefits of DEL Innovation

May 6, 2022

The last two years have seen X-Chem transform itself from a boutique DEL screening shop to an integrated drug discovery...


Getting Back to In Person

April 13, 2022

I recently had the pleasure of taking a trip to the West Coast to meet with several X-Chem clients. They...


A Track Record of Success

March 15, 2022

For those who didn’t notice, X-Chem underwent a major rebranding in mid-2021. We rolled out our new website, logo, color...