X-Chem Is Your Partner in Small Molecule Drug Discovery

X-Chem is the partner you need to unlock exponential possibilities in your small molecule drug discovery. Our scientists deploy DNA-encoded library (DEL) technology, medicinal chemistry and artificial intelligence (AI) to deliver exponentially better drug discovery solutions.

X-Chem offers services, products, and solutions that can help accelerate all aspects of drug discovery, from screen to candidate. Work with our industry-leading scientists to get the most our of our powerful technologies. At X-Chem, our mission is to help our clients get medicines to patients faster.

With over 100 libraries comprising more than 250 billion DNA-tagged compounds, we wield a vast index of identifiable small molecules. This reach enables you to investigate a hugely diverse range of chemistry that holds enormous potential. At a success rate of 80% in identifying functional hits, we deliver for our partners and clients. To date we have licensed nearly 100 discovery programs, comprising over 300 indepedent chemical series and more than 1000 validated hit compounds.

Our AI platform for drug discovery — ArtemisAI — is built from proprietary data that is 10 times larger than public sources. ArtemisAI allows DEL-based model generation, generative modeling, property prediction and access to physics-based approaches, all within a single, intuitive user interface. Its predictive models have unmatched accuracy in predicting key physicochemical and absorption, distribution, metabolism, and excretion (ADME) parameters. X-Chem’s extensive experience in medicinal chemistry ensures that our technologies are seamlessly integrated to deliver hits, leads and candidates, faster, for our clients.

X-Chem’s versatile technology is proven in projects spanning 30 target classes. These include challenging categories such as protein-protein interactions (PPI), bacterial targets, ubiquitin ligases, epigenetic targets and G protein-coupled receptors (GPCR). Whether you are a DEL practitioner or an investigator looking for quality hit compounds against a novel target, we will help you leverage our platform, technology and expertise in the best way possible. Find more hits, faster, then transition from hit to candidate with our revolutionary combination of AI, DEL and medicinal chemistry.

100+ libraries with 250 billion DNA-tagged compounds

Success rate of 80% in identifying functional hits

Solutions and products that meet your needs

Mission

To leverage the world’s leading drug discovery platform to help create molecules that will improve human health.

Vision

Be the leading drug discovery partner in a world made healthier by X-Chem’s scientific innovation and novel technologies.

Values

Innovation: Explore new frontiers in science to cultivate growth, value and greater efficiency — both for X-Chem and its partners.

Collaboration: Provide an open mind and candid, solution-oriented feedback to help partners be successful.

Integrity: Bring candor and accountability to every decision, and act with unwavering ethics.

Excellence: Never settle when greater accomplishments are within reach, and seek to exceed expectations by embracing new challenges.

Empowerment: Listen, share and collaborate to cultivate better decision-making.

Our Global Footprint

With locations in North America and Europe, we operate state-of-the-art facilities, fully equipped to support all aspects of drug discovery, and staffed by passionate and experienced scientists.

Get Ready for Dynamic Drug Discovery

Set yourself up for success with X-Chem’s XD3 — Dynamic Drug Discovery — empowered by ArtemisAI. Blending the power of DEL, medicinal chemistry and AI to help you achieve your discovery goals.