Available Compounds
Beyond DNA-Encoded Libraries

While X-Chem is known for our pioneering DNA-encoded libraries (DELs), we are leaders in custom and synthetic chemistry. You can access novel and diverse small molecules by purchasing our building block intermediates or screening compounds. Both options provide high-quality small molecules to jump-start your drug discovery process.

Screening Compounds

Our screening compounds set represents a diverse and versatile collection for early phase drug discovery. Our on-the-shelf system guarantees that all the compounds are readily available. All the compounds listed strictly correspond to the physical – chemical parameters:

202 ≤ MW (g mol ¹) < 600
-4.5 ≤ LogP ≤ 7.8
HBA = 1-11
HBD = 0-5
Heavy atom count = 15-43
Number of aromatic rings = 0-6
Rotatable bond count (RBS) = 1-13
TPSA = 15-155

Average physical – chemical parameters
Molecular weight (g mol ¹) = 340.736
LogDpH7.4 = 0.209
LogP = 1.071
HBA = 4.4
HBD = 0.94
TPSA = 68.8
fsp³ = 0.555
Rotatable bond count (RBS) = 4.87
Heavy atom count = 24.65
No. of aromatic ring count = 1.84

Download X-Chem’s SD File for Screening Compounds*

*Must have SD compatible software to extract file