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Design concepts for DNA-Encoded Library synthesis

May 1, 2021

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Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening

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Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy

March 8, 2021

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Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition

February 4, 2021

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Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

December 20, 2020

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Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

July 25, 2020

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Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding

July 11, 2020

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Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry.

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Asymmetric Synthesis of a Potent CXCR7 Modulator Featuring a Hindered Tertiary β-Amino Amide Stereocenter

August 15, 2018

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Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target

January 9, 2018